This is an RFC-822 compliant address:
Tim Colson <tcolson@cisco.com>

This is RFC-822..been around for over 20 years... explains how email addresses should look, feel, smell, taste.
http://www.faqs.org/rfcs/rfc822.html

This is what is put into the Reply-To header by JIRA:
Reply-To: Tim, Colson, tcolson@cisco.com

Which is correctly, albeit badly, interpreted by an RFC822 compliant email app as THREE addresses – two of which will fail.
Tim; Colson; tcolson@cisco.com

Naughty Jira.
Timo