Macros are cool features, but the current method of invoking them could be a lot better.

From an ease of use standpoint, I would like to put often-used macros directly in the "insert more" menu (or the context menu for "{") with macro attributes pre-set to match my needs. I did figure out that I could search in the context menu for "{" which is great, but still not perfect since I could find no way except using the mouse (click on the macro box and then click edit) to click an option check box for the macro (which pretty much negates the ease of inserting a macro that way).

It is nice that you can highlight text and it will wrap the macro around that but only if you go the long, click-heavy, route of using the Insert-more-content menu, and (with some difficulty) you can copy/paste macro insertions with the attributes set, but it obviously then also comes with the existing text data as well. It seems like there could be some syntax that would let me invoke a macro myself. Something like {macro:No Markup, nopanel="true"}text{macro} or something, which I could paste from the clipboard (I would paste only the initial {macro...} and then move to the end of the text I wanted to wrap and put in the ending code).

I'm guessing this from other comments that hint that maybe you used to be able to do that, and, in fact, your own wiki-markup tutorial mentions {color:red}text{color} which works in Jira, but apparently no longer works in the wiki (if it ever did). All-in-all I really wish you would provide a "wiki markup" view of the page, so that I could edit all the codes myself (like Wikimedia does) even if you translate them in and out of the codes under the hood to some internal format.