Jira Response Slow

Hi
We experience very slow response for Jira
From the logs we have the following issues
10/11/2004 06:30:03,057 ERROR [event.listeners.search.IssueIndexListener]-----78 Times
Error re-indexing Issue[GenericEntity:Issue]
[created,2004-10-11 06:29:14.857][summary,trouble with WSAD][timeoriginalestimate,null][workflowId,19227][component,null][fixfor,null][type,3][timespent,null][environment,][status,1][resolution,null][updated,2004-10-11 06:30:02.906][id,19187][timeestimate,null][key,OWEB-306][description,Could you please uninstall
10/11/2004 05:39:58,822 ERROR [jira.issue.index.DefaultIndexManager] — 152 times
IOException getting file path to write to Lock obtain timed
FIELD, OLDVALUE, OLDSTRING, NEWVALUE, NEWSTRING FROM changeitem WHERE FIELD=? AND OLDSTRING=?ORDER BY groupid desc ([Microsoft][SQLServer 2000 Driver for JDBC][SQLServer]The text, ntext, and image data types cannot be compared or sorted, except when using IS NULL or LIKE operator.)

10/11/2004 06:29:15,337 ERROR [jira.issue.index.DefaultIndexManager] ---- 51 - times
Problem with path /Data/ispdeployapps/jira/mssqlindex/issues:Lock obtain timed out

10/11/2004 03:16:56,595 ERROR [workflow.function.issue.IssueReindexFunction]
Could not reindex issue: com.atlassian.jira.issue.index.IndexException:
Problem with path /Data/ispdeployapps/jira/mssqlindex/issues: Lock 10/11/2004 00:11:34,534 ERROR [workflow.function.issue.IssueReindexFunction]
Could not reindex issue:com.atlassian.jira.issue.index.IndexException:IOException:java.io.IOException:Lock obtain timed