Greetings,
I upgraded Confluence from 1.4 to 2.2 about two weeks ago. Since then there has been a problem: About every 24hrs, Confluence will exhibit a problem with loading the appropriate CSS sheets. This will display an html page sans any style sheets. The only way to get this resolved (until the next 24hrs) is to restart the Resin application which in turn restarts both Confluence and Jira - /usr/share/resin/webapps/(Confluence)(Jira)

Configuration details:
I have Jira 3.6.1 and Confluence 2.2 running as webapps under Resin 2.1.16. I recently upgraded from Confluence 1.4 where this issue was not present.
System information:
Java startup variables: args="-J-Xms256m -Xmx1g -XX:MaxPermSize=256m -Djava.awt.headless=true -Dorg.apache.commons.logging.simplelog
.defaultlog=info"
Java Version 1.5.0_06
Java Vendor Sun Microsystems Inc.
JVM Version 1.0
JVM Vendor Sun Microsystems Inc.
JVM Implementation Version 1.5.0_06-b05
Java Runtime Java(TM) 2 Runtime Environment, Standard Edition
Java VM Java HotSpot(TM) 64-Bit Server VM
User Timezone US/Pacific
Operating System Linux 2.6.5-7.97-smp
OS Architecture amd64
Filesystem Encoding UTF-8

Java VM Memory Statistics
Total Memory 411 MB
Free Memory 212 MB
Used Memory 199 MB
Memory Graph
[Used Memory ( 48 %)] [Free Memory ( 52 %)]
52 % Free

Runtime Information
Database Dialect bucket.dialect.MySQLDialect
Database Connection URL jdbc:mysql://localhost/confluence?autoReconnect=true
Database Driver Name com.mysql.jdbc.Driver
Database Driver Version 3.1
Application Server Resin/2.1.16
Servlet Version 2.3
Confluence Home /var/confluence-conf
Uptime 29 minutes, 28 seconds
Version 2.2
Build Number 512

So far it was suggested from Confluence support to roll back any themes I may have enabled. However, I am using all defualt themes and layouts:

Main Layout
Defines the generic header and footer for all pages in Confluence.
Edit | Reset Default | View Default
Global Layout
Defines the appearance of the dashboard and a users profile.
< default > | Create custom | View Default
Popup Layout
Popup windows such as the user history popup are displayed using this layout.
< default > | Create custom | View Default
Printable Layout
The layout used to display the page when the user clicks the "printable" icon in the top-right of the page.
< default > | Create custom | View Default
Content Layouts

Content layouts control the appearance of content such as pages and news items: they don't change the way the pages themselves are displayed, but they allow you to alter the way the surrounding comments or attachments are shown.
Decorator Operations
Space Layout
Controls how a space is displayed.
< default > | Create custom | View Default
Page Layout
Controls how a page is displayed.
< default > | Create custom | View Default
Mail Layout
Controls how mail is displayed.
< default > | Create custom | View Default
Blog Post Layout
Controls how a blog post is displayed.
< default > | Create custom | View Default

This issue is reproduceable about every 24 hours regardless of the browser/version being used. I will get a screenshot the next time it happens if that would help. I have also attached two log files that I hope wil help.

Thanks in advance and let me know if you require additional information.

-Jesse